Article
Hypermethylation of two consecutive tumor suppressor genes, BLU and RASSF1A, located at 3p21.3 in cervical neoplasias.
Gynecologic oncology - 1 Mar 2007
Lai Hung-Cheng, Lin Ya-Wen, Chang Cheng-Chang, Wang Hui-Chen, Chu Ta-Wei, Yu Mu-Hsien, Chu Tang-Yuan
Abstract excerpt
OBJECTIVES: Although initiated by human papillomavirus (HPV), cervical carcinogenesis demands other cofactors to shape its natural course. Epigenetic effects such as DNA methylation, are considered to contribute to carcinogenesis process. METHODS: The methylation status of BLU and RASSF1A, as wel...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
