Article
Mutational analysis of KRAS and its clinical implications in cervical cancer patients.
Journal of gynecologic oncology - 1 Jan 2018
Jiang Wei, Xiang Libing, Pei Xuan, He Tiancong, Shen Xuxia, Wu Xiaohua, Yang Huijuan
Abstract excerpt
OBJECTIVE: The predictive and prognostic role of KRAS mutations in cervical cancer remains inconclusive. The aim of this study was to explore the clinicopathological and prognostic relevance of KRAS mutations in invasive cervical cancers (ICC). METHODS: Reverse transcription polymerase chain reaction (PCR) and Sanger sequencing were employed to detect KRAS mutations in 876 ICC patients. Quantitative real-time PCR...
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