Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inverse correlation between EGFR mutation and FHIT, RASSF1A and RUNX3 methylation in lung adenocarcinoma: relation with smoking status.

Anticancer research - 1 Apr 2011

Yanagawa Naoki, Tamura Gen, Oizumi Hiroyuki, Endoh Makoto, Sadahiro Mitsuaki, Motoyama Teiichi

Abstract excerpt

BACKGROUND: Epidemiological studies have demonstrated a causal link between tobacco smoking and lung cancer. However, lung adenocarcinoma (AC) is also frequently found in non-smokers compared with other non-small cell lung carcinoma (NSCLC) subtypes. MATERIALS AND METHODS: Mutations of both epith...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acid Anhydride Hydrolases
Share to Core Binding Factor Alpha 3 Subunit
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenomics

Share to Genes, Tumor Suppressor

Share to Polymorphism, Single-Stranded Conformational

Share to Smoking

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 21508367

Genes

EGFR
FHIT
KRAS
RUNX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21508367-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inverse correlation between EGFR mutation and FHIT, RASSF1A and RUNX3 methylation in lung adenocarcinoma: relation with smoking status.PMID 21508367Read ↗

Association of RASSF1A promoter methylation with lung cancer risk: a meta-analysis.Semantic proximity Read ↗

Promoter methylations of RASSF1A and p16 is associated with clinicopathological features in lung cancers.Semantic proximity Read ↗

Epigenetic effects of lung cancer predisposing factors impact on clinical diagnosis and prognosisSemantic proximity Read ↗

Molecular characterization of chronic obstructive pulmonary disease-related non-small cell lung cancer through aberrant methylation and alterations of EGFR signaling.Semantic proximity Read ↗

Association between Retinoic acid receptor-β hypermethylation and NSCLC risk: a meta-analysis and literature review.Semantic proximity Read ↗

The role of DNA methylation and DNA methyltransferases (DNMTs) as potential biomarker and therapeutic target in non-small cell lung cancer (NSCLC)Semantic proximity Read ↗

Quantitative promoter hypermethylation analysis of RASSF1A in lung cancer: comparison with methylation-specific PCR technique and clinical significance.Semantic proximity Read ↗

From tobacco smoking to mutational signature: the role of epigenetic changes in human cancersSemantic proximity Read ↗

Methylation of L1RE1, RARB, and RASSF1 function as possible biomarkers for the differential diagnosis of lung cancerSemantic proximity Read ↗

Quantitative assessment of lung cancer associated with genes methylation in the peripheral blood.Semantic proximity Read ↗

RASSF1A promoter methylation and Kras2 mutations in non small cell lung cancer.Semantic proximity Read ↗

Wif1 hypermethylation as unfavorable prognosis of non-small cell lung cancers with EGFR mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.