Article
RASSF1A promoter methylation and Kras2 mutations in non small cell lung cancer.
Neoplasia (New York, N.Y.) - 1 Jan 2000
Li Jie, Zhang Zhongqiu, Dai Zunyan, Popkie Anthony P, Plass Christoph, Morrison Carl, Wang Yian, You Ming
Abstract excerpt
In the present studies, we investigated the correlation between RASSF1A promoter methylation status and Kras2 mutations in 65 primary non small cell lung cancer (NSCLC) including 33 adenocarcinomas, 12 large cell carcinomas, and 20 squamous cell carcinomas. Mutational analysis of Kras2 showed: 30% (10 of 33) of adenocarcinomas, 25% (3 of 12) of large cell carcinomas, and only 5% (1 of 20) of squamous cell...
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