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Acquisition of i.v. cocaine self-administration in adolescent and adult male rats selectively bred for high and low saccharin intake.

Physiology & behavior - 16 May 2007

Perry Jennifer L, Anderson Marissa M, Nelson Sarah E, Carroll Marilyn E

Abstract excerpt

Adolescence and excessive intake of saccharin have each been previously associated with enhanced vulnerability to drug abuse. In the present study, we focused on the relationship between these two factors using male adolescent and adult rats selectively bred for high (HiS) and low (LoS) levels of saccharin intake. On postnatal day 25 (adolescents) or 150 (adults), rats were implanted with an intravenous catheter...

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Cocaine-Related Disorders
Conditioning, Operant
Data Interpretation, Statistical
Drinking
Eating

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Self Administration

Substance Abuse, Intravenous

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Identifiers

PMID: 17360010
DOI: 10.1016/j.physbeh.2007.02.001
PMCID: PMC4965876

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