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Article

Adolescent nicotine exposure sensitizes cue-induced reinstatement of cocaine seeking in rats bred for high and low saccharin intake.

Drug and alcohol dependence - 1 Oct 2011

Anker Justin J, Carroll Marilyn E

Abstract excerpt

BACKGROUND: Environmental factors such as early drug exposure influence drug abuse vulnerability, and evidence also suggests that drug abuse is highly heritable. The purpose of the present study was to determine whether environmental and genetic factors interact to produce additive drug abuse vulnerability. METHODS: An animal model of relapse was used to examine the effects of adolescent nicotine exposure on...

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PMID: 21439737
DOI: 10.1016/j.drugalcdep.2011.02.016

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