Impulsivity on a Go/No-go task for intravenous cocaine or food in male and female rats selectively bred for high and low saccharin intake.

doi:10.1097/FBP.0b013e32830dc0ae

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Article

Impulsivity on a Go/No-go task for intravenous cocaine or food in male and female rats selectively bred for high and low saccharin intake.

Behavioural pharmacology - 1 Sept 2008

Anker Justin J, Gliddon Luke A, Carroll Marilyn E

Abstract excerpt

The purpose of this study was to examine a form of impulsive behavior (impaired inhibition) using cocaine or food reward in addiction-prone and addiction-resistant rats that were bred for high saccharin (HiS) or low saccharin (LoS) intake, respectively. A Go/No-go procedure was used to examine cocaine and food reinforcement (Go component) and the inhibition of responding during a subsequent period of nonreward...

Topics

Animals
Cocaine
Cocaine-Related Disorders
Dose-Response Relationship, Drug
Feeding Behavior
Female
Impulsive Behavior
Infusions, Intravenous
Inhibition, Psychological
Male
Motivation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Rats

Rats, Sprague-Dawley

Reinforcement Schedule

Saccharin

Selection, Genetic

Self Administration

Source

Open in PubMed

Identifiers

PMID: 18690116
DOI: 10.1097/FBP.0b013e32830dc0ae

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