Back to search

Article

A translational rodent model of individual differences in sensitivity to the aversive properties of ethanol

2023-06-09

Abstract excerpt

<h4>Background</h4> A strong relationship exists between individual sensitivity to the aversive properties of ethanol and risk for alcohol use disorder (AUD). Despite this, our understanding of the neurobiological mechanisms underlying subjective response to ethanol is relatively poor. A major contributor to this is the absence of preclinical models that enable exploration of this individual variability similar t...

Identifiers and source

Literature Corpus work
b6e1d4a9-ff53-53ef-9a0d-eacf8ac14512
DOI
10.1101/2023.06.08.544209
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A translational rodent model of individual differences in sensitivity to the aversive properties of ethanolDOI 10.1101/2023.06.08.544209
Selective breeding for differential saccharin intake as an animal model of drug abuse.Semantic proximity
An operant ethanol self-administration paradigm that discriminates between appetitive and consummatory behaviors reveals distinct behavioral phenotypes in commonly used rat strains.Semantic proximity
Ethanol withdrawal and proclivity are inversely related in rats selectively bred for differential saccharin intake.Semantic proximity
Assessment of the aversive and rewarding effects of alcohol in Fischer and Lewis rats.Semantic proximity
Large-scale characterization of cocaine addiction-like behaviors reveals that escalation of intake, aversion-resistant responding, and breaking-points are highly correlated measures of the same constructSemantic proximity
Parametric Characterization of a Taste Phenotype in Rats Selectively Bred for High Versus Low Saccharin Intake.Semantic proximity
Individual difference in addiction-like behaviors and choice between cocaine versus food in Heterogeneous Stock ratsSemantic proximity
A Novel Single-Fish Assay for Ethanol Self-Administration in ZebrafishSemantic proximity
Individual differences in oxycodone addiction-like behaviors in a large cohort of heterogeneous stock (HS) ratsSemantic proximity
Dissociation between the aversive and pharmacokinetic effects of ethanol in female Fischer and Lewis rats.Semantic proximity
Intravenous cocaine and heroin self-administration in rats selectively bred for differential saccharin intake: phenotype and sex differences.Semantic proximity
Ivermectin Reduces Withdrawal-Induced Alcohol Intake via CeA GABAergic EnhancementSemantic proximity
Select a neighboring publication to make it the new centre.