Article
Food dependence in rats selectively bred for low versus high saccharin intake. Implications for "food addiction".
Appetite - 1 Oct 2011
Yakovenko Veronica, Speidel Elizabeth R, Chapman Clinton D, Dess Nancy K
Abstract excerpt
The "food addiction" concept implies that proneness to drug dependence and to food dependence should covary. The latter was studied in low- (LoS) and high- (HiS) saccharin-consuming rats, who differ in drug self-administration (HiS>LoS) and withdrawal (LoS>HiS). Sugary food intake in the first 1-2 h was higher in HiS than LoS rats. Sugar intake predicted startle during abstinence only among LoS rats. These...
Topics
- Animals
- Behavior, Addictive
- Dietary Carbohydrates
- Ethanol
- Female
- Glucose
- Phenotype
- Rats
- Rats, Inbred Strains
- Reflex, Startle
- Saccharin
- Self Administration