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Article

Cytokine genotype and phenotype effects on lung function decline in firefighters.

Journal of occupational and environmental medicine - 1 Mar 2007

Josyula Arun B, Kurzius-Spencer Margaret, Littau Sally R, Yucesoy Berran, Fleming James, Burgess Jefferey L

Abstract excerpt

OBJECTIVE: We conducted this study to evaluate the association of cytokine genotypes and sputum concentrations on longitudinal decline in lung function in firefighters. METHODS: In 67 firefighters with at least four pulmonary function tests, DNA was analyzed for functional polymorphisms of interleukin (IL)-1beta, IL-1 receptor antagonist (IL-1RA), IL-8, IL-10, tumor necrosis factor-alpha (TNF-alpha) genes, and...

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Source

Identifiers

PMID: 17351514
DOI: 10.1097/JOM.0b013e3180322584

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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