TNF polymorphisms modify endotoxin exposure-associated longitudinal lung function decline.

doi:10.1136/oem.2006.029025

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Article

TNF polymorphisms modify endotoxin exposure-associated longitudinal lung function decline.

Occupational and environmental medicine - 1 Jun 2007

Zhang Hongxi, Hang Jingqing, Wang Xiaorong, Zhou Wei, Sun Bixiong, Dai Helian, Su Li, Christiani David C

Abstract excerpt

OBJECTIVES: Endotoxin exposure induces airway inflammation, hyper-responsiveness and higher expression of tumour necrosis factor (TNF). This study was conducted to investigate whether TNF polymorphisms modify the effect of endotoxin exposure on chronic declines in lung function. METHODS: Associations between TNF and LTA polymorphisms, endotoxin exposure and lung function were analysed in 263 cotton workers and...

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PMID: 17332138
DOI: 10.1136/oem.2006.029025
PMCID: PMC2078509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.