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Article

Mechanisms of CD4 Downregulation by the Nef and Vpu Proteins of Primate Immunodeficiency Viruses

28 Feb 2007

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1), human immunodeficiency virus type 2 (HIV-2), and simian immunodeficiency virus (SIV) are the etiological agents of acquired immunodeficiency syndrome (AIDS) in humans and a related disease in non-human primates. These viruses infect T cells and macrophages that express the surface glycoprotein, CD4, because this glycoprotein acts as a co-receptor for incoming virus...

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Identifiers

PMID: 17346169
DOI: 10.2174/156652407780059177

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Mechanisms of CD4 Downregulation by the Nef and Vpu Proteins of Primate Immunodeficiency VirusesPMID 17346169Read ↗

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