Article
Development of an automated SNP analysis method using a paramagnetic beads handling robot.
Biotechnology and bioengineering - 1 Oct 2007
Hagiwara Hiroko, Sawakami-Kobayashi Kazumi, Yamamoto Midori, Iwasaki Shoji, Sugiura Mika, Abe Hatsumi, Kunihiro-Ohashi Sumiko, Takase Kumiko, Yamane Noriko, Kato Kaoru, Son Renkon, Nakamura Michihiro, Segawa Osamu, Yoshida Mamiko, Yohda Masafumi, Tajima Hideji, Kobori Masato, Takahama Yousuke, Itakura Mitsuo, Machida Masayuki
Abstract excerpt
Biological and medical importance of the single nucleotide polymorphism (SNP) has led to development of a wide variety of methods for SNP typing. Aiming for establishing highly reliable and fully automated SNP typing, we have developed the adapter ligation method in combination with the paramagnetic beads handling technology, Magtration(R). The method utilizes sequence specific ligation between the fluorescently...
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