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Article

Magnetic Bead Processing Enables Sensitive Ligation-Based Detection of HIV Drug Resistance Mutations.

Analytical chemistry - 8 Feb 2022

Nelson Dalton J, Leelawong Mindy, Pask Megan E, Wester C William, Aliyu Muktar H, Haselton Frederick R

Abstract excerpt

HIV develops single nucleotide polymorphisms (SNPs), some of which lead to drug resistance mutations (DRMs) that prevent therapeutic viral suppression. Genomic sequencing enables healthcare professionals to select effective combination antiretroviral therapy (ART) to achieve and maintain viral suppression. However, sequencing technologies, which are resource-intensive, are limited in their availability. This...

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Identifiers

PMID: 35077642
DOI: 10.1021/acs.analchem.1c05040
PMCID: PMC11127743

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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