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Article

A study of molecular signals deregulating mismatch repair genes in prostate cancer compared to benign prostatic hyperplasia.

PloS one - 1 Jan 2015

Basu Sanmitra, Majumder Subhadipa, Bhowal Ankur, Ghosh Alip, Naskar Sukla, Nandy Sumit, Mukherjee Subhabrata, Sinha Rajan Kumar, Basu Keya, Karmakar Dilip, Banerjee Soma, Sengupta Sanghamitra

Abstract excerpt

Prostate cancer is one of the leading causes of mortality among aging males. There is an unmet requirement of clinically useful biomarkers for early detection of prostate cancer to reduce the liabilities of overtreatment and accompanying morbidity. The present population-based study investigates the factors disrupting expression of multiple functionally related genes of DNA mismatch repair pathway in prostate...

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Identifiers

PMID: 25938433
DOI: 10.1371/journal.pone.0125560
PMCID: PMC4418837

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DNMT1

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