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GSTP1 positive prostatic adenocarcinomas are more common in Black than White men in the United States

30 Jun 2021

Abstract excerpt

GSTP1 is a member of the Glutathione-S-transferase (GST) family silenced by CpG island DNA hypermethylation in 90-95% of prostate cancers. However, prostate cancers expressing GSTP1 have not been well characterized. We used immunohistochemistry against GSTP1 to examine 1673 primary prostatic adenocarcinomas on tissue microarrays (TMAs) with redundant sampling from the index tumor from prostatectomies. GSTP1...

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PMID: 34191807
DOI: 10.1371/journal.pone.0241934

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