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Article

Genetic variation at the TNF locus and the risk of severe sequelae of ocular Chlamydia trachomatis infection in Gambians.

Genes and immunity - 1 Jun 2007

Natividad A, Hanchard N, Holland M J, Mahdi O S M, Diakite M, Rockett K, Jallow O, Joof H M, Kwiatkowski D P, Mabey D C W, Bailey R L

Abstract excerpt

Tumor necrosis factor (TNF) is thought to be a key mediator of the inflammatory and fibrotic response to Chlamydia trachomatis (Ct) infection. A large matched-pair case-control study investigated putative functional single nucleotide polymorphisms (SNPs) across the major histocompatibility complex (MHC) class III region, including TNF and its immediate neighbors nuclear factor of kappa light polypeptide gene...

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Source

Identifiers

PMID: 17330135
DOI: 10.1038/sj.gene.6364384

Genes

TNF
LTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Genetic variation at the TNF locus and the risk of severe sequelae of ocular Chlamydia trachomatis infection in Gambians.PMID 17330135Read ↗

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