Article
Beta1-subunits increase surface expression of a large-conductance Ca2+-activated K+ channel isoform.
Journal of neurophysiology - 1 May 2007
Kim Eun Young, Zou Shengwei, Ridgway Lon D, Dryer Stuart E
Abstract excerpt
Auxiliary (beta) subunits of large-conductance Ca(2+)-activated K(+) (BK(Ca)) channels regulate the gating properties of the functional channel complex. Here we show that an avian beta1-subunit also stimulates the trafficking of BK(Ca) channels to the plasma membrane in HEK293T cells and in a nat...
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