Article

Characterization of an early-diverging KCNE potassium-channel auxiliary subunit in the jawless vertebrate lamprey

2026-05-01

Abstract excerpt

The KCNE (KCNE1–6) proteins are single-pass transmembrane auxiliary subunits of the voltage-gated K + channel KCNQ1. KCNQ1–KCNE complexes have been well studied in jawed vertebrates ranging from zebrafish to humans, but KCNE subunits from earlier-diverging vertebrates remain poorly characterized. Here, we functionally characterize a single KCNE-like gene in lamprey, a jawless vertebrate, and designate it kcne0 a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0c250307-061d-5c05-937d-15e7bbda2273
DOI: 10.64898/2026.04.28.721385

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Characterization of an early-diverging KCNE potassium-channel auxiliary subunit in the jawless vertebrate lampreyDOI 10.64898/2026.04.28.721385Read

In vitro molecular interactions and distribution of KCNE family with KCNQ1 in the human heartSemantic proximity Read

KCNQ potassium channels: physiology, pathophysiology, and pharmacology.Semantic proximity Read

Molecular cloning and functional expression of KCNQ5, a potassium channel subunit that may contribute to neuronal M-current diversity.Semantic proximity Read

Evolutionary analysis of vertebrate KCNH voltage-gated potassium channels and their expression in zebrafish embryosSemantic proximity Read

Distribution and functional properties of human KCNH8 (Elk1) potassium channelsSemantic proximity Read

Functional coassembly of KCNQ4 with KCNE-beta- subunits in Xenopus oocytes.Semantic proximity Read

Beta1-subunits increase surface expression of a large-conductance Ca2+-activated K+ channel isoform.Semantic proximity Read

Cloning of a New Mouse Two-P Domain Channel Subunit and a Human Homologue with a Unique Pore StructureSemantic proximity Read

KCNQ-like Potassium Channels in Caenorhabditis elegansSemantic proximity Read

A potassium channel (Kv4) cloned from the heart of the tunicate Ciona intestinalis and its modulation by a KChIP subunit.Semantic proximity Read

WTC deafness Kyoto (dfk): a rat model for extensive investigations of Kcnq1 functions.Semantic proximity Read

Evolution and diversity of mammalian sodium channel genes.Semantic proximity Read