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Article

Enigma homolog 1 scaffolds protein kinase D1 to regulate the activity of the cardiac L-type voltage-gated calcium channel.

Cardiovascular research - 1 Jun 2008

Maturana Andrés D, Wälchli Sébastien, Iwata Miki, Ryser Stephan, Van Lint Johannes, Hoshijima Masahiko, Schlegel Werner, Ikeda Yasuhiro, Tanizawa Katsuyuki, Kuroda Shun'ichi

Abstract excerpt

AIMS: In cardiomyocytes, protein kinase D1 (PKD1) plays a central role in the response to stress signals. From a yeast two-hybrid assay, we have identified Enigma Homolog 1 (ENH1) as a new binding partner of PKD1. Since in neurons, ENH1, associated with protein kinase Cepsilon, was shown to modulate the activity of N-type calcium channels, and the pore-forming subunit of the cardiac L-type voltage-gated calcium...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Calcium Channels, L-Type

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Source

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Identifiers

PMID: 18296710
DOI: 10.1093/cvr/cvn052
PMCID: PMC3241959

Genes

PKD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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