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Article

No association between the PREP gene and lithium responsive bipolar disorder.

BMC psychiatry - 26 Feb 2007

Mamdani Firoza, Sequeira Adolfo, Alda Martin, Grof Paul, Rouleau Guy, Turecki Gustavo

Abstract excerpt

BACKGROUND: Bipolar disorder (BD) is a major psychiatric condition that commonly requires prophylactic and episodic treatment. Lithium (Li) has been used for over 40 years now as an effective prophylactic agent. Response to Li treatment seems to be, at least in part, genetically determined. Although we ignore how Li specifically prevents mood episodes, it has previously been suggested that Li exerts an effect on...

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Identifiers

PMID: 17324276
DOI: 10.1186/1471-244X-7-9
PMCID: PMC1810534

Genes

PREP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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