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Article

Lithium: a key to the genetics of bipolar disorder

1 Jan 2009

Abstract excerpt

Since the 1950s, lithium salts have been the main line of treatment for bipolar disorder (BD), both as a prophylactic and as an episodic treatment agent. Like many psychiatric conditions, BD is genetically and phenotypically heterogeneous, but evidence suggests that individuals who respond well to lithium treatment have more homogeneous clinical and molecular profiles. Response to lithium seems to cluster in...

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PMID: 19691823
DOI: 10.1186/gm79

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