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Article

Exploring Genetic Variability at PI, GSK3, HPA, and Glutamatergic Pathways in Lithium Response: Association With IMPA2, INPP1, and GSK3B Genes.

Journal of clinical psychopharmacology - 1 Oct 2015

Mitjans Marina, Arias Bárbara, Jiménez Esther, Goikolea Jose M, Sáiz Pilar A, García-Portilla M Paz, Burón Patricia, Bobes Julio, Vieta Eduard, Benabarre Antoni

Abstract excerpt

Lithium is considered the first-line treatment in bipolar disorder, although response could range from an excellent response to a complete lack of response. Response to lithium is a complex phenotype in which different factors, part of them genetics, are involved. In this sense, the aim of this study was to investigate the potential association of genetic variability at genes related to phosphoinositide, glycogen...

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Source

Identifiers

PMID: 26267417
DOI: 10.1097/JCP.0000000000000382

Genes

IMPA2
INPP1
GRIK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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