Article
Lithium response and genetic variation in the CREB family of genes.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jun 2008
Mamdani Firoza, Alda Martin, Grof Paul, Young L Trevor, Rouleau Guy, Turecki Gustavo
Abstract excerpt
Bipolar disorder (BD) is a severe psychiatric disorder that affects 1% of the population. Recently, there have been many attempts to identify specific genes that are involved in BD; however, the task of finding susceptibility genes is not easy due to the complexity of the disorder. Since lithium (Li) has been used for over 40 years now as an effective prophylactic agent and response to Li treatment seems to be,...
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