Article
A Role of Lipophilic Peptidoglycan-related Molecules in Induction of Nod1-mediated Immune Responses
24 Feb 2007
Abstract excerpt
Nod1 is an intracellular protein that is involved in recognition of bacterial molecules and whose genetic variation has been linked to several inflammatory diseases. Previous studies suggested that the recognition core of Nod1 stimulatory molecules is gamma-D-glutamyl-meso-diaminopimelic acid (iE-DAP), but the identity of the major Nod1 stimulatory molecule produced by bacteria remains unknown. Here we show that...
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