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Article

Roles of Peptidoglycan Recognition Protein (PGRP) in Immunity and Implications for Novel Anti-infective Measures

1 Jan 2012

Abstract excerpt

Peptidoglycan recognition protein (PGRP) is an important host innate immunity arm capable of peptidoglycan and allied bacteria recognition. PGRP belongs to host pattern recognition receptors (PRRs) responsible for pathogen associated molecular patterns recognition, such as lipopolysaccharide, lipoteichoic acid, PGN, and mannose. As an essential host PRR, PGRP is well conserved from insects to mammals. The...

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PMID: 23140167
DOI: 10.1615/critreveukargeneexpr.v22.i3.90

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