Structure and interactions of the first three RNA recognition motifs of splicing factor prp24.

doi:10.1016/j.jmb.2007.01.078

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Structure and interactions of the first three RNA recognition motifs of splicing factor prp24.

Journal of molecular biology - 13 Apr 2007

Bae Euiyoung, Reiter Nicholas J, Bingman Craig A, Kwan Sharon S, Lee Donghan, Phillips George N, Butcher Samuel E, Brow David A

Abstract excerpt

The essential Saccharomyces cerevisiae pre-messenger RNA splicing protein 24 (Prp24) has four RNA recognition motifs (RRMs) and facilitates U6 RNA base-pairing with U4 RNA during spliceosome assembly. Prp24 is a component of the free U6 small nuclear ribonucleoprotein particle (snRNP) but not the U4/U6 bi-snRNP, and so is thought to be displaced from U6 by U4/U6 base-pairing. The interaction partners of each of...

Topics

Amino Acid Motifs
Amino Acid Sequence
Models, Molecular
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
Protein Binding
Protein Structure, Secondary
RNA Splicing
RNA, Fungal
RNA, Small Nuclear
RNA-Binding Proteins
Ribonucleoproteins, Small Nuclear

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Sequence Homology, Amino Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 17320109
DOI: 10.1016/j.jmb.2007.01.078
PMCID: PMC1939982

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.