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Article

Reduced cortical bone mass in mice with inactivation of interleukin-4 and interleukin-13.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jun 2007

Silfverswärd Carl-Johan, Larsson Sune, Ohlsson Claes, Frost Anders, Nilsson Olle

Abstract excerpt

The aim of the present study was to study the in vivo role of IL-4 and IL-13 on bone metabolism. The skeletal phenotypes of male and female IL-13(-/-) (n = 7+7), IL-4(-/-)IL-13(-/-) (n = 7+7), and WT (n = 7+7) mice were compared. Analysis was made at 6 weeks of age (juvenile) by pQCT, and at 20 w...

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PMID: 17318894
DOI: 10.1002/jor.20361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17318894-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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