Article
Are glutathione S-transferase gene polymorphisms linked to neonatal jaundice?
European journal of pediatrics - 1 Jan 2008
Muslu Necati, Dogruer Zeynep Nil, Eskandari Gulcin, Atici Aytug, Kul Seval, Atik Ugur
Abstract excerpt
Glutathione S-transferases (GSTs) are a major group of phase II detoxification enzymes involved in the metabolism of both endogenous and xenobiotic compounds. In addition to their catalytic function in detoxification, GSTs participate in binding to nonsubstrate ligands such as bilirubin. Ligandin, which is one of the principal hepatic-binding proteins, is also a member of the GST family. The aim of the present...
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