Expression of class mu glutathione-S-transferase in human liver and its association with hepatopathies.

doi:10.1002/ajmg.a.20364

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Article

Expression of class mu glutathione-S-transferase in human liver and its association with hepatopathies.

American journal of medical genetics. Part A - 15 Dec 2003

Engracia V, Leite M M B S, Pagotto R C, Zucoloto S, Barbosa C A A, Mestriner M A

Abstract excerpt

We studied the distribution of GSTM1 phenotypes in 611 individuals from an ethnically mixed sample of the Brazilian population who died from various causes. No influence of age, gender, or ethnicity was detected on the phenotypic distribution. In a sub-sample of 66 alcoholic individuals compared with 399 non-alcoholics there was almost a doubling of the odds ratio for GSTM1(0) individuals in the alcoholic...

Topics

Alcoholism
Brazil
Female
Gene Expression Regulation, Enzymologic
Gene Frequency
Genetic Predisposition to Disease
Genotype
Glutathione Transferase
Humans
Liver
Liver Diseases
Male
Odds Ratio
Phenotype

Source

Open in PubMed

Identifiers

PMID: 14608647
DOI: 10.1002/ajmg.a.20364

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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