Article
GSTP1 and CYP2B6 Genetic Polymorphisms and the Risk of Bronchopulmonary Dysplasia in Preterm Neonates.
American journal of perinatology - 1 Jul 2017
Zachaki Sophia, Daraki Aggeliki, Polycarpou Elena, Stavropoulou Chrysa, Manola Kalliopi N, Gavrili Stavroula
Abstract excerpt
Objectives Antioxidant response plays a key role in bronchopulmonary dysplasia (BPD) pathogenesis. The glutathione-S-tranferases pi 1 (GSTP1) and cytochrome P450 (CYP) detoxification enzymes protect cells from oxidative damage. The aim of the study was to investigate whether the A313G GSTP1 and G516T CYP2B6 inactivating polymorphisms could be associated with BPD susceptibility. Study Design To test this...
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