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Article

Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection.

Nature reviews. Immunology - 1 Sept 2018

Simmons Jason D, Stein Catherine M, Seshadri Chetan, Campo Monica, Alter Galit, Fortune Sarah, Schurr Erwin, Wallis Robert S, Churchyard Gavin, Mayanja-Kizza Harriet, Boom W Henry, Hawn Thomas R

Abstract excerpt

Mycobacterium tuberculosis is a leading cause of mortality worldwide and establishes a long-lived latent infection in a substantial proportion of the human population. Multiple lines of evidence suggest that some individuals are resistant to latent M. tuberculosis infection despite long-term and intense exposure, and we term these individuals 'resisters'. In this Review, we discuss the epidemiological and genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29895826
DOI: 10.1038/s41577-018-0025-3
PMCID: PMC6278832

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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