Article
Type 1 T-regulatory cells: their role in the control of immune responses.
Transplantation - 15 May 2003
Groux Hervé
Abstract excerpt
The induction of tolerance is essential for the maintenance of immune homeostasis, for the prevention of autoimmune diseases, and to achieve transplantation tolerance. To induce tolerance, the immune system uses several mechanisms, including the deletion of autoreactive T cells, the induction of anergy, and active suppression of autoimmune responses. The mechanisms of thymic deletion and anergy of autoreactive T...
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