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Article

Defining features of protective CD4 T cell responses to Mycobacterium tuberculosis.

Current opinion in immunology - 1 Aug 2014

Sakai Shunsuke, Mayer-Barber Katrin D, Barber Daniel L

Abstract excerpt

CD4 T cells are critical for control of Mycobacterium tuberculosis (Mtb) infection and represent the best hope for vaccine-elicited protection. However, little is understood about the properties of Mtb-specific CD4 T cells that mediate control, and the lack of correlates of protection present a significant barrier to the rational development of new vaccination and therapeutic strategies which are sorely needed....

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Identifiers

PMID: 25000593
DOI: 10.1016/j.coi.2014.06.003
PMCID: PMC4122329

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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