Article
Cryopreservation of mature monocyte-derived human dendritic cells for vaccination: influence on phenotype and functional properties.
Cancer immunology, immunotherapy : CII - 1 Mar 2003
Westermann Jörg, Körner Ida J, Kopp Joachim, Kurz Steffen, Zenke Martin, Dörken Bernd, Pezzutto Antonio
Abstract excerpt
In the past decade there has been increasing evidence that tumor antigen-loaded dendritic cells (DC) are able to elicit anti-tumor T-cell responses. Initial clinical data for different tumor entities are encouraging, with objective tumor regressions being observed in some patients. Since GMP prod...
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