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Article

gag as well as myc sequences contribute to the transforming phenotype of the avian retrovirus FH3.

Journal of virology - 1 Feb 1992

Tikhonenko A T, Linial M L

Abstract excerpt

The avian retrovirus FH3, like MC29 and CMII, encodes a Gag-Myc fusion protein. However, the FH3-encoded protein is larger, about 145 kDa, and contains almost the entire retroviral gag gene. In contrast to the other gag-myc avian retroviruses, FH3 fails to transform fibroblasts in vitro, although macrophages are transformed both in vitro and in vivo (C. Chen, B. J. Biegalke, R. N. Eisenman, and M. L. Linial, J....

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Identifiers

PMID: 1731115
DOI: 10.1128/JVI.66.2.946-955.1992
PMCID: PMC240796

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