Article
gag as well as myc sequences contribute to the transforming phenotype of the avian retrovirus FH3.
Journal of virology - 1 Feb 1992
Tikhonenko A T, Linial M L
Abstract excerpt
The avian retrovirus FH3, like MC29 and CMII, encodes a Gag-Myc fusion protein. However, the FH3-encoded protein is larger, about 145 kDa, and contains almost the entire retroviral gag gene. In contrast to the other gag-myc avian retroviruses, FH3 fails to transform fibroblasts in vitro, although...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Transformation, Neoplastic
- Cells, Cultured
- Chick Embryo
- Chickens
- Cloning, Molecular
- Embryo, Nonmammalian
- Genes, gag
- Genes, myc
- Genetic Vectors
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Phenotype
- Polymerase Chain Reaction
- Quail
- RNA, Viral