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FCRL1 immunoregulation in B cell development and malignancy

25 Sept 2023

Abstract excerpt

Immunotherapeutic targeting of surface regulatory proteins and pharmacologic inhibition of critical signaling pathways has dramatically shifted our approach to the care of individuals with B cell malignancies. This evolution in therapy reflects the central role of the B cell receptor (BCR) signaling complex and its co-receptors in the pathogenesis of B lineage leukemias and lymphomas. Members of the Fc...

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PMID: 37822931
DOI: 10.3389/fimmu.2023.1251127

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