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Article

The tumor necrosis factor alpha -308 G/A polymorphism does not influence inflammation and coagulation response in human endotoxemia.

Shock (Augusta, Ga.) - 1 Mar 2007

Kovar Florian M, Marsik Claudia, Cvitko Tuende, Wagner Oswald F, Jilma Bernd, Endler Georg

Abstract excerpt

Tumor necrosis factor (TNF)-alpha plays a major role in the immune system. Release of proinflammatory cytokines, such as TNF-alpha and interleukin 6, by macrophages and other cells occurs in response to bacterial products. It has been reported that the TNF-alpha -308 G/A polymorphism in the TNF-alpha gene determines basal TNF-alpha levels. We hypothesized that it may also be associated with the degree of...

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Source

Identifiers

PMID: 17304103
DOI: 10.1097/01.shk.0000239768.64786.3a

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The tumor necrosis factor alpha -308 G/A polymorphism does not influence inflammation and coagulation response in human endotoxemia.PMID 17304103Read ↗

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