Article
Relation between the tumor necrosis factor-alpha (TNF-alpha) gene and protein expression, and clinical, biochemical, and genetic markers: age, body mass index and uric acid are independent predictors for an elevated TNF-alpha plasma level in a complex risk model.
European cytokine network - 1 Jan 2000
Schulz Susanne, Schagdarsurengin Undraga, Suss Thomas, Müller-Werdan Ursula, Werdan Karl, Gläser Christiane
Abstract excerpt
BACKGROUND: Tumor necrosis factor-alpha (TNF-alpha) has been implicated in the pathogenesis of numerous complex diseases. The plasma level of this pro-inflammatory cytokine is associated with a variety of different risk factors, but little is known about the genetic background and the complex interactions. METHODS: in this clinical study, correlations were studied between plasma levels of circulating TNF-alpha...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.