Article
Ethnicity-specific gene-gene interaction between IL-13 and IL-4Ralpha among African Americans with asthma.
American journal of respiratory and critical care medicine - 1 May 2007
Battle Natalie C, Choudhry Shweta, Tsai Hui-Ju, Eng Celeste, Kumar Gunjan, Beckman Kenneth B, Naqvi Mariam, Meade Kelley, Watson H George, Lenoir Michael, Burchard Esteban González
Abstract excerpt
RATIONALE: Genes in the interleukin (IL)-4/IL-13/IL-4Ralpha pathway have been shown to be associated with asthma and related phenotypes in some populations, but not in others. Furthermore, interaction between these genes has been shown to affect asthma in white and Chinese populations. OBJECTIVES: To determine whether there are IL-4/IL-13 and IL-4Ralpha gene-gene interactions that are associated with asthma in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
