Article
Interleukin 13 and interleukin 4 receptor-α polymorphisms in rhinitis and asthma.
International archives of allergy and immunology - 1 Jan 2010
Bottema Renske W B, Nolte Ilja M, Howard Timothy D, Koppelman Gerard H, Dubois Anthony E J, de Meer Gea, Kerkhof Marjan, Bleecker Eugene R, Meyers Deborah A, Postma Dirkje S
Abstract excerpt
BACKGROUND: Asthma and rhinitis may represent two manifestations of the same airway disease. Genetic research can increase our understanding of their common or distinct pathogenesis. IL13 and IL4R polymorphisms are associated with asthma and show gene-gene interaction in asthma. Their role in rhinitis has not been extensively studied. METHODS: Association of IL13 and IL4R polymorphisms in relation to rhinitis,...
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