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Article

Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma.

American journal of human genetics - 1 Jan 2002

Howard Timothy D, Koppelman Gerard H, Xu Jianfeng, Zheng Siqun L, Postma Dirkje S, Meyers Deborah A, Bleecker Eugene R

Abstract excerpt

Asthma is a common respiratory disease that is characterized by variable airways obstruction caused by acute and chronic bronchial inflammation; associated phenotypes include bronchial hyperresponsiveness (BHR), elevated total serum immunoglobulin E (IgE) levels, and skin tests positive to common allergens. Binding of interleukin-13 (IL13) or interleukin-4 (IL4) to the IL4 receptor (IL4R) induces the initial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11709756
DOI: 10.1086/338242
PMCID: PMC384891

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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