Article
Fleshing out filaggrin phenotypes.
The Journal of investigative dermatology - 1 Mar 2007
Irvine Alan D
Abstract excerpt
The association of filaggrin null alleles with eczema has been replicated in several European populations. Three large, well-conducted studies confirm this association and offer insights into the phenotypic nature of eczema associated with these alleles. Early data suggest that FLG-associated eczema may be more persistent, more likely to have palmar hyperlinearity, and more likely to be associated with asthma....
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