Article
Association of ALDH1 promoter polymorphisms with alcohol-related phenotypes in Trinidad and Tobago.
Journal of studies on alcohol and drugs - 1 Mar 2007
Moore Shelly, Montane-Jaime Karelia, Shafe Samuel, Joseph Roma, Crooks Helene, Carr Lucinda G, Ehlers Cindy L
Abstract excerpt
OBJECTIVE: Two polymorphisms in the promoter region of the gene encoding cytosolic aldehyde dehydrogenase (ALDH1A1), ALDH1A1*2 and ALDH1A1*3, have recently been identified. The present study sought to determine whether an association exists between ALDH1A1 genotypes, alcohol dependence, drinking history, and liver function tests in the two major ethnic groups of Trinidad and Tobago (TT). METHOD: The participants...
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