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Article

Evaluation of aldehyde dehydrogenase 1 promoter polymorphisms identified in human populations.

Alcoholism, clinical and experimental research - 1 Sept 2003

Spence John P, Liang Tiebing, Eriksson C J Peter, Taylor Robert E, Wall Tamara L, Ehlers Cindy L, Carr Lucinda G

Abstract excerpt

BACKGROUND: Cytosolic aldehyde dehydrogenase, or ALDH1A1, functions in ethanol detoxification, metabolism of neurotransmitters, and synthesis of retinoic acid. Because the promoter region of a gene can influence gene expression, the ALDH1A1 promoter regions were studied to identify polymorphism, to assess their functional significance, and to determine whether they were associated with a risk for developing...

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Identifiers

PMID: 14506398
DOI: 10.1097/01.ALC.0000087086.50089.59
PMCID: PMC4560114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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