Article
Association of the ALDH1A1*2 promoter polymorphism with alcohol phenotypes in young adults with or without ALDH2*2.
Alcoholism, clinical and experimental research - 1 Jan 2013
Otto Jacqueline M, Hendershot Christian S, Collins Susan E, Liang Tiebing, Wall Tamara L
Abstract excerpt
BACKGROUND: Prior studies suggest a possible association of a promoter polymorphism in the ALDH1A1 gene ( ALDH1A1*2 ) with alcohol use or dependence. The aim of this study was to examine the association of ALDH1A1*2 with drinking behaviors in Asian young adults and to examine ALDH2 genotype as a potential moderator of these associations. METHODS: Asian young adults (n = 951) were recruited from 2 college sites...
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