Article
Impact of the alcohol-dehydrogenase (ADH) 1C and ADH1B polymorphisms on drinking behavior in nonalcoholic Japanese.
Human mutation - 1 May 2007
Matsuo Keitaro, Hiraki Akio, Hirose Kaoru, Ito Hidemi, Suzuki Takeshi, Wakai Kenji, Tajima Kazuo
Abstract excerpt
A linkage disequilibrium (LD) between the alcohol-dehydrogenase 1B (ADH1B) and alcohol-dehydrogenase 1C (ADH1C) polymorphisms adds complexity to differentiating the significance of these two genetic polymorphisms on drinking behavior and alcoholism. We have recently shown the importance of the ADH1B polymorphism on habitual drinking in the Japanese population; however, the issue regarding the LD between the ADH1B...
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