Strong association of the alcohol dehydrogenase 1B gene (ADH1B) with alcohol dependence and alcohol-induced medical diseases.

doi:10.1016/j.biopsych.2011.02.024

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Article

Strong association of the alcohol dehydrogenase 1B gene (ADH1B) with alcohol dependence and alcohol-induced medical diseases.

Biological psychiatry - 15 Sept 2011

Li Dawei, Zhao Hongyu, Gelernter Joel

Abstract excerpt

BACKGROUND: The alcohol dehydrogenase 1B gene (ADH1B) is hypothesized to affect predisposition to alcohol dependence (AD) and abuse. A variant of the ADH1B gene (rs1229984 or Arg48His; previously referred to as Arg [*1] and His [*1]) has been reported to be associated with reduced rates of alcohol and drug dependence. Different studies have produced inconclusive results regarding association between rs1229984 (or...

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Alcohol Consumption and Health Effects
Alcohol Dehydrogenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Alcoholism

Alcoholism and Thiamine Deficiency

Ethnicity

Genetic Association Studies

Genetic Predisposition to Disease

Substance Abuse Treatment and Outcomes

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PMID: 21497796
DOI: 10.1016/j.biopsych.2011.02.024
PMCID: PMC3142297

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