Article
Beta-globin intergenic transcription and histone acetylation dependent on an enhancer.
Molecular and cellular biology - 1 Apr 2007
Kim Aeri, Zhao Hui, Ifrim Ina, Dean Ann
Abstract excerpt
Histone acetyltransferases are associated with the elongating RNA polymerase II (Pol II) complex, supporting the idea that histone acetylation and transcription are intertwined mechanistically in gene coding sequences. Here, we studied the establishment and function of histone acetylation and transcription in noncoding sequences by using a model locus linking the beta-globin HS2 enhancer and the embryonic...
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