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Article

Parkin polymorphisms and environmental exposure: decrease in age at onset of Parkinson's disease.

Neurotoxicology - 1 May 2007

Ghione Isabella, Di Fonzo Alessio, Saladino Francesca, Del Bo Roberto, Bresolin Nereo, Comi Giacomo Pietro, Rango Mario

Abstract excerpt

We tested the hypothesis that parkin polymorphisms (SNPs) and environmental exposure (EE) interact to reduce the age of onset of idiopathic Parkinson disease (PD). We prospectively and consecutively enrolled a total of 81 Italian PD patients. The diagnosis of PD was based on the UK Parkinson's Disease Society's brain bank criteria. Twenty-one patients with a positive family history for PD or tremor were excluded...

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Identifiers

PMID: 17335904
DOI: 10.1016/j.neuro.2007.01.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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